4.5 Article

Polyarylated Thiazoles via a Combined Halogen Dance - Cross-Coupling Strategy

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2009, Issue 19, Pages 3228-3236

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200900092

Keywords

Protein kinase inhibitor analogues; Halogen dance; Cross-coupling; Palladium; Polyarylated thiazoles

Funding

  1. Higher Education Commission (HEC)
  2. Pakistan and Austria Student Exchange Program (OEAD)

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The application of the halogen dance reaction for the synthesis of starting materials for cross-coupling reactions is reported. The obtained compounds were then successfully applied in sequential Stille and Suzuki-Miyaura cross-coupling reactions to obtain novel thiazole derivatives. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

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