Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2009, Issue 3, Pages 358-363Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200800791
Keywords
Enzyme catalysis; Laccase; Lipase; Michael addition; Cascade reaction; Quinones
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Funding
- IPST@GT
- Royal Thai Government Scholarship
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A laccase-lipase cocatalytic system was used to catalyze the domino reaction between catechols and nucleophilic reagents including 1,3-dicarbonyl compounds and aromatic amines in aqueous medium at room temperature. Lipase acted as a catalyst for Michael addition step, and also enhanced the overall yield of the final products. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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