Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2008, Issue 34, Pages 5673-5685Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200800686
Keywords
NMR spectroscopy; Configuration determination; Conformation analysis; Residual dipolar couplings
Categories
Funding
- Fonds der Chemischen Industrie and the Deutsche Forschungsgeminschaft (DFG)
Ask authors/readers for more resources
After the huge impact that residual dipolar Couplings (RDCs) have had oil the Structure determination of biological macromolecules by NMR spectroscopy, their utility in the structure determination of small/medium-sized organic compounds is more and more recognised. This microreview will provide a short overview on how to introduce the anisotropic environment necessary to measure RDCs, the corresponding measurement methods and the applications for the determination of the relative configurations and the assignment of diastereotopic moieties. Their application to rigid compounds will be described, as will their very promising application to more flexible compounds, which is an area in which RDCs are expected to yield information that is not accessible by any other NMR spectroscopic means. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available