4.5 Article

Straightforward synthesis of fluorinated amphiphilic thiols

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2008, Issue 19, Pages 3308-3313

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200800113

Keywords

synthesis design; sulfur; thiols; amphiphiles; fluorine

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C8-perfluoroalkyl thiols bearing a polyoxyethylene chain of variable length were prepared in good yields following a straightforward synthetic strategy. These thiols are soluble in organic solvents of different polarities from chloroform to methanol. The thiol with a PEG550 chain shows very good solubility in water. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).

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