A fluorescence-enhanced chemodosimeter for Fe3+ based on hydrolysis of bis(coumarinyl) Schiff base

Bis(coumarinyl) Schiff base I was designed and synthesized as a fluorescence turn-on chemodosimeter for Fe3+. The chemodosimeter was readily synthesized in four steps from 2,4-dihydroxybenzaldehyde. The addition of Fe3+ to chemodosimeter 1 induced about a 140-fold enhancement in fluorescence. Furthermore, chemorlosimeter 1 was also highly selective to Fe3+ over other metal ions, and most of the related metals ions exhibited negligible detection interference. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).