Three-component indium-mediated domino allylation of 1H-indole-3-carbaldehyde with electron-rich (hetero)arenes:: Highly efficient access to variously functionalized indolylbutenes

We have developed a three-component, one-pot domino reaction that combines the allylindation of 1H-indole-3-carbaldehyde with the dehydrative alkylation of stabilized C nucleophiles (e.g., electron-rich heteroarenes, electron-rich aromatics, and stabilized enols) or N nucleophiles (e.g., azoles). ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).