Journal
EUROPEAN JOURNAL OF NUTRITION
Volume 52, Issue 1, Pages 337-345Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00394-012-0340-6
Keywords
Red meat; Whole grain; Biomarkers; Glucose metabolism
Categories
Funding
- Federal Ministry of Education and Research, Germany (Bundesministerium fur Bildung und Forschung) [Forderkennzeichen 0315381A]
Ask authors/readers for more resources
To examine the association of red meat and whole-grain bread consumption with plasma levels of biomarkers related to glucose metabolism, oxidative stress, inflammation and obesity. Our cross-sectional study was based on 2,198 men and women who were selected as a sub-cohort for an investigation of biological predictors of diabetes and cardiovascular diseases from the European Prospective Investigation into Cancer and Nutrition-Potsdam study. Circulating levels of glycated hemoglobin, adiponectin, hs-CRP, gamma-glutamyltransferase, alanine-aminotransferase, fetuin-A, HDL-cholesterol and triglycerides were measured from random blood samples. Diet and lifestyle data were assessed by questionnaires, and anthropometric data were measured. After multivariable adjustment, higher consumption of whole-grain bread was significantly (P trend < 0.05) associated with lower levels of GGT, ALT and hs-CRP, whereas higher consumption of red meat was significantly associated with higher levels of GGT and hs-CRP when adjusted for potential confounding factors related to lifestyle and diet. Further adjustment for body mass index and waist circumference attenuated the association between red meat and hs-CRP (P = 0.19). The results of this study suggest that high consumption of whole-grain bread is related to lower levels of GGT, ALT and hs-CRP, whereas high consumption of red meat is associated with higher circulating levels of GGT and hs-CRP.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available