Journal
EUROPEAN JOURNAL OF NEUROLOGY
Volume 21, Issue 1, Pages 167-170Publisher
WILEY-BLACKWELL
DOI: 10.1111/ene.12081
Keywords
amphetamines; cocaine; epidemiology; epilepsy; epileptic seizures; illicit drugs; marijuana
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Background and purposeThis study aimed to assess the prevalence of illicit drug use among epilepsy patients and its effects on the disease. MethodsWe systematically interviewed epilepsy outpatients at a tertiary epilepsy clinic. Predictors for active cannabis use were analysed with a logistic regression model. ResultsOverall, 310 subjects were enrolled; 63 (20.3%) reported consuming cannabis after epilepsy was diagnosed, and 16 (5.2%) used other illicit drugs. Active cannabis use was predicted by sex (male) [odds ratio (OR) 5.342, 95% confidence interval (95% CI) 1.416-20.153] and age (OR 0.956, 95% CI 0.919-0.994). Cannabis consumption mostly did not affect epilepsy (84.1%). Seizure worsening was observed with frequent illicit (non-cannabis) drug use in 80% of cases. ConclusionsCannabis use does not seem to affect epilepsy; however, frequent use of other drugs increases seizure risk.
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