Journal
EUROPEAN JOURNAL OF NEUROLOGY
Volume 18, Issue 12, Pages 1373-1378Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1468-1331.2011.03512.x
Keywords
entacapone; motor control; Parkinson's disease; rasagiline
Categories
Funding
- Teva Pharmaceutical Industries
- H Lundbeck A/S
- Teva
- Lundbeck
- GlaxoSmithKline
- Boehringer Ingleheim
- Newron
- Merck Serono
- Novartis
- Impax
- Schering Plough
- Chiesi pharma
- UCB
- Teva Pharmaceutical Industries Ltd
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Background: The LARGO study demonstrated that rasagiline 1 mg/day as adjunct to levodopa significantly reduces OFF time to the same magnitude as adjunct entacapone. This substudy of LARGO aimed to assess the effect of rasagiline and entacapone on the motor symptoms of PD during the practically defined OFF state.
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