Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 45, Issue 5, Pages 2044-2047Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2010.01.023
Keywords
Imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyrrolo[3,2-c]pyridine; BVDV activity; Antiviral
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Funding
- (Fonds voor Wetenschappelijk Onderzoek, Vlaanderen) FWO
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A series of imidazo[1,2-a]pyrrolo[2,3-c]pyridines has been prepared and evaluated for their anti-BVDV activities in MDBK cells. From the synthesized analogues bearing modifications of the substituents at positions 2, 3, 7 and 8, compounds 10a, b, 16, 24, 25 and 26 exhibited significant anti-BVDV activities. (C) 2010 Elsevier Masson SAS. All rights reserved.
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