Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 43, Issue 11, Pages 2380-2385Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2008.01.019
Keywords
Organotin; Spectra; Salicylaldehyde; Adenine; Schiff base
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Funding
- University of Bayreuth Germany
- EJ Institute of Chemistry and University of Karachi (Pakistan)
- University of Thessalonki, Greece
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Five novel organotin(IV) derivatives have been synthesized by refluxing trimethyl, triethyl, tributyl, and triphenyl and tribenzyltin chloride with Schiff base derived from salicylaldehyde and adenine. These compounds were characterized by spectroscopic (IR, H-1, C-13, Sn-119-NMR, Sn-119 Mossbauer) techniques and elemental analysis. Based on these results, trigonal bipyramidal geometry is suggested. The synthesized compounds were also treated with various microorganisms and found to be active. (C) 2008 Elsevier Masson SAS. All rights reserved.
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