Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 43, Issue 5, Pages 1081-1084Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2007.06.019
Keywords
iproplatin; reactive form of iproplatin; anticancer agent; glutathione-platinum(II) complex; Pt(IV) reduction
Categories
Ask authors/readers for more resources
The reaction of iproplatin with reduced glutathione at different mole ratios yielded cis-di(isopropylamine)chloro-glutathionatoplatinum(H), not the expected cis-dichloro-species, indicating a mode of action of this anticancer agent that is different from that of cis-diamminedichloroplatinum(II). (C) 2007 Elsevier Masson SAS. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
