4.7 Article

Chemotherapy of leishmaniasis part-VIII: Synthesis and bioevaluation of novel chalcones

Journal

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 43, Issue 11, Pages 2473-2478

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2007.12.014

Keywords

Dihydro-alpha-ionone; Chalcones; In vitro antileishmanial activity

Funding

  1. MOH (India)

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Some novel dihydro-a-ionone based chalcones have been synthesized and evaluated for their in vitro antileishmanial activity in promastigote and amastigote model. Some of the compounds showed 100% inhibition at 5 and 2 mu m/ml concentration. (C) 2008 Elsevier Masson SAS. All rights reserved.

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