Journal
ANNALS OF HEPATOLOGY
Volume 14, Issue 6, Pages 924-928Publisher
MEXICAN ASSOC HEPATOLOGY
DOI: 10.5604/16652681.1171785
Keywords
Cholesterol; Granuloma; Hepatitis; Pseudohyponatremia; Electrophoresis
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Lipoprotein X (LpX) is an abnormal lipoprotein associated with cholestasis. It is a significant cause of severe hypercholesterolemia and should always be considered in patients with cholestatic liver disease. This case highlights the significance of LpX as a cause of severe hypercholesterolemia in a patient with cholestasis secondary to a granulomatous hepatitis attributed to tuberculosis. Lipoprotein agarose gel electrophoresis and gradient get electrophoresis were performed for the detection of LpX. The liver function tests, electrolytes, lipid profile and bile acids were also determined. Anti-tuberculous therapy was initiated and the liver functions improved with normalisation of the lipid profile.
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