Journal
EUROPEAN JOURNAL OF IMMUNOLOGY
Volume 41, Issue 9, Pages 2490-2493Publisher
WILEY
DOI: 10.1002/eji.201141792
Keywords
Inflammation; Innate immunity; Macrophages
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Funding
- Japanese Ministry of Education, Culture, Sports, Science and Technology
- Ministry of Health, Labour and Welfare in Japan
- Japan Society for the Promotion of Science (JSPS)
- Grants-in-Aid for Scientific Research [20002008] Funding Source: KAKEN
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Epigenetic control of gene expression is critical for cellular differentiation and development. Macrophage development, polarization and activation are also controlled by DNA and histone modifications. This Viewpoint summarizes the recent findings on the role of histone modifications regulating macrophage polarization toward M1 and M2 subtypes.
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