Related references
Note: Only part of the references are listed.Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
John S. Tzartos et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: Role of intracellular osteopontin
Mari L. Shinohara et al.
IMMUNITY (2008)
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
Marco Prinz et al.
IMMUNITY (2008)
The type IIFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
Beichu Guo et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
A rush to judgment on Th17
Lawrence Steinman
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
New targets for treatment of multiple sclerosis
Lawrence Steinman
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Beta interferon restricts the inflammatory potential of CD4+ cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells
Francisco M. Martin-Saavedra et al.
MOLECULAR IMMUNOLOGY (2008)
A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T-H-17 responses
Elisabetta Volpe et al.
NATURE IMMUNOLOGY (2008)
IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner
Lai Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Successful treatment of collagen-induced arthritis in non-human primates by chimeric anti-osteopontin antibody
Nobuchika Yamamoto et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2007)
An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity1
Timothy J. Harris et al.
JOURNAL OF IMMUNOLOGY (2007)
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Roza Nurieva et al.
NATURE (2007)
IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells
Akihiro Kimura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
IL-6-gp130-STAT3 in T cells directs the development of IL-17+Th with a minimum effect on that of Treg in the steady state
Mika Nishihara et al.
INTERNATIONAL IMMUNOLOGY (2007)
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
Xuexian O. Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
Lawrence Steinman
NATURE MEDICINE (2007)
Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells
Eun Mi Hur et al.
NATURE IMMUNOLOGY (2007)
Multiple sclerosis: a complicated picture of autoimmunity
Henry F. McFarland et al.
NATURE IMMUNOLOGY (2007)
Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia
Elisabeth Kamphuis et al.
BLOOD (2006)
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
Ivaylo I. Ivanov et al.
CELL (2006)
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
Yutaka Komiyama et al.
JOURNAL OF IMMUNOLOGY (2006)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli et al.
NATURE (2006)
Transforming growth factor-β induces development of the TH17 lineage
PR Mangan et al.
NATURE (2006)
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
M Veldhoen et al.
IMMUNITY (2006)
T-bet-dependent expression of osteopontin contributes to T cell polarization
ML Shinohara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
H Park et al.
NATURE IMMUNOLOGY (2005)
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
LE Harrington et al.
NATURE IMMUNOLOGY (2005)
Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype
AC Renkl et al.
BLOOD (2005)
Role of magnetic resonance imaging and immunotherapy in treating multiple sclerosis
JW Zhang et al.
ANNUAL REVIEW OF MEDICINE (2005)
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
CL Langrish et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Plasma osteopontin levels in multiple sclerosis
M Comabella et al.
JOURNAL OF NEUROIMMUNOLOGY (2005)
Different effects of simvastatin and interferon beta on the proteolytic activity of matrix metalloproteinases
BC Kieseier et al.
ARCHIVES OF NEUROLOGY (2004)
Osteopontin levels and increased disease activity in relapsing-remitting multiple sclerosis patients
MHJ Vogt et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
Alternative activation of STAT1 and STAT3 in response to interferon-γ
YL Qing et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Interferon-β-1b decreased matrix metalloproteinase-9 serum levels in primary progressive multiple sclerosis
M Yushchenko et al.
JOURNAL OF NEUROLOGY (2003)
Stat1 functions as a attenuator of Runx2 in the transcriptional program of osteoblast cytoplasmic differentiation
S Kim et al.
GENES & DEVELOPMENT (2003)
Elevated osteopontin levels in active relapsing-remitting multiple sclerosis
MHJ Vogt et al.
ANNALS OF NEUROLOGY (2003)
Transcriptional analysis of targets in multiple sclerosis
L Steinman et al.
NATURE REVIEWS IMMUNOLOGY (2003)
Osteopontin polymorphisms and disease course in multiple sclerosis
S Caillier et al.
GENES AND IMMUNITY (2003)
IFN-g induction of osteopontin expression in human monocytoid cells
XF Li et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2003)
Immune regulatory properties and interactions of Copolymer-I and beta-interferon 1a in multiple sclerosis
Y Zang et al.
JOURNAL OF NEUROIMMUNOLOGY (2003)
A comparison of the mechanisms of action of interferon beta and glatiramer acetate in the treatment of multiple sclerosis
JW Zhang et al.
CLINICAL THERAPEUTICS (2002)
Cutting edge: Attenuated experimental autoimmune encephalomyelitis in Eta-1/osteopontin-deficient mice
M Jansson et al.
JOURNAL OF IMMUNOLOGY (2002)
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
D Chabas et al.
SCIENCE (2001)
Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks
AW O'Regan et al.
IMMUNOLOGY TODAY (2000)
IFN-β induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7
J Sancéau et al.
ONCOGENE (2000)
Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
CQ Chu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Eta-1 (osteopontin): An early component of type-1 (cell-mediated) immunity
S Ashkar et al.
SCIENCE (2000)