Journal
EUROPEAN JOURNAL OF IMMUNOLOGY
Volume 38, Issue 11, Pages 2934-2937Publisher
WILEY-BLACKWELL
DOI: 10.1002/eji.200838760
Keywords
Education; NK-cell; Quantitative; Reversibility; Tolerance
Categories
Funding
- Swedish Cancer Society
- Swedish Research Council
- Karolinska Institutet
- Swedish Foundation for Strategic Research
- MD/PhD position at the Karolinska Institutet
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In this article, we will move beyond the current controversy of different models for NK-cell education and instead discuss the properties characterizing MHC class I-guided functional development of NK cells. We will argue that this development, which represents the endpoint of NK-cell education, is a quantitative and dynamic, and perhaps even reversible, process.
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