Journal
EUROPEAN JOURNAL OF EPIDEMIOLOGY
Volume 33, Issue 11, Pages 1033-1047Publisher
SPRINGER
DOI: 10.1007/s10654-018-0426-4
Keywords
Body mass index; Waist circumference; Waist-to-hip ratio; Diabetes; Physical activity; Kidney stones; Systematic review; Meta-analysis; Cohort studies
Categories
Funding
- Imperial College National Institute of Health Research (NIHR) Biomedical Research Centre (BRC)
Ask authors/readers for more resources
We conducted a systematic review and meta-analysis to clarify the association between adiposity, diabetes, and physical activity and the risk of kidney stones. PubMed and Embase were searched up to April 22nd 2018 for relevant studies. Summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated using random effects models. Thirteen cohort studies were included. The summary relative risk was 1.21 (95% CI 1.12-1.30, I-2=76%, n=8) per 5 unit increment in BMI, 1.16 (95% CI 1.12-1.19, I-2=0%, n=5) per 10cm increase in waist circumference, 1.06 (95% CI 1.04-1.08, I-2=67%, n=3) per 5kg increase in weight and 1.12 (95% CI 1.06-1.18, I-2=86%, n=3) per 5kg of weight gain. The summary RR was 1.16 (95% CI 1.03-1.31, I-2=51%, n=10) for participants with diabetes compared to participants without diabetes, and 0.93 (95% CI 0.78-1.10, I-2=80%, n=4) for high vs. low physical activity. These results suggest a positive association between adiposity and diabetes and the risk of kidney stones, but no association with physical activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available