Journal
EUROPEAN JOURNAL OF CLINICAL NUTRITION
Volume 64, Issue 4, Pages 436-438Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ejcn.2009.159
Keywords
Salba; whole grain; glycemia; appetite
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Funding
- Salba Corporation S.A, Buenos Aires, Argentina
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Despite strong correlations linking whole-grain consumption to reductions in heart disease, the physiological mechanisms involved remain ambiguous. We assessed whether Salba (Salvia Hispanica L.) whole grain reduces postprandial glycemia in healthy subjects, as a possible explanation for its cardioprotective effects observed in individuals with diabetes. The study used acute, randomized, double-blind, controlled design in which 11 healthy individuals (6 males and 5 females; body mass index 22.3 +/- 2.8 kg/m(2)) received 0, 7, 15 or 24 g of Salba baked into white bread. Capillary samples and appetite ratings were collected over 2 h after consumption. A dose-response reduction in postprandial glycemia (P = 0.002, r(2) = 0.203) was observed with all three doses of Salba, significantly decreasing incremental areas under the curve (iAUCs) and time point-specific blood glucose (P<0.05). Appetite ratings were decreased at 60 min after high, 90 min after high and intermediate and at 120 min after all treatments (P<0.05). Decrease in postprandial glycemia provides a potential explanation for improvements in blood pressure, coagulation and inflammatory markers previously observed after 12-week Salba supplementation in type II diabetes. European Journal of Clinical Nutrition (2010) 64, 436-438; doi: 10.1038/ejcn.2009.159; published online 20 January 2010
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