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C-reactive protein is a bystander of cardiovascular disease

Journal

EUROPEAN HEART JOURNAL
Volume 31, Issue 17, Pages 2092-U25

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/eurheartj/ehq242

Keywords

C-reactive protein

Funding

  1. Michael G. DeGroote/Heart and Stroke Foundation of Ontario Chair in Population Health
  2. May Cohen Eli Lilly Chair in Women's Health Research
  3. Heart and Stroke Foundation Chair in Cardiovascular Research

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A large number of studies have evaluated the association of hs-C-reactive protein with atherosclerosis and coronary heart disease (CHD) in mechanistic, genetic, population-based studies, as well as clinical trials. This paper reviews the collective evidence to determine if hs-C-reactive protein is part of the causal pathway of atherosclerosis and CHD or whether it is a bystander.

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