Journal
EUKARYOTIC CELL
Volume 12, Issue 4, Pages 470-481Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/EC.00364-12
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Funding
- INCRECyT fellowship from Parque Cientifico y Tecnologico de Albacete
- junta de comunidades de Castilla-La Mancha (JCCM)
- Deutsche Forschungsgemeinschaft (DFG) [WE 3537/1-2]
- PHRI startup funds
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Understanding the pathogenesis of an infectious disease is critical for developing new methods to prevent infection and diagnose or cure disease. Adherence of microorganisms to host tissue is a prerequisite for tissue invasion and infection. Fungal cell wall adhesins involved in adherence to host tissue or abiotic medical devices are critical for colonization leading to invasion and damage of host tissue. Here, with a main focus on pathogenic Candida species, we summarize recent progress made in the field of adhesins in human fungal pathogens and underscore the importance of these proteins in establishment of fungal diseases.
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