Journal
EPILEPSY RESEARCH
Volume 87, Issue 1, Pages 88-94Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.eplepsyres.2009.06.006
Keywords
Subcortical heterotopia; Infancy; Surgery; Drug-resistant epilepsy; Cognitive delay
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The clinical, radiological, neurophysiological and neuropsychological findings of three patients with giant subcortical heterotopia are reported. All patients experienced psychomotor and behaviour improvement after surgery. Two subjects are seizure-free after complete excision of the heterotopia; the third patient significantly improved following subtotal removal (Engel's class II). Patients affected by giant subcortical heterotopias can have a favourable prognosis after the surgical removal of the malformation, even following long-lasting epilepsy. (C) 2009 Elsevier B.V. All rights reserved.
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