Journal
EPILEPSIA
Volume 52, Issue 6, Pages 1052-1057Publisher
WILEY
DOI: 10.1111/j.1528-1167.2011.03041.x
Keywords
Epilepsy; Cause; Classification; Etiology; Idiopathic epilepsy; Symptomatic epilepsy; Provoked epilepsy
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Funding
- Department of Health's NIHR Biomedical Research Centre
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The etiology of epilepsy is a major determinant of clinical course and prognosis, yet the current classifications of epilepsy do not list etiology in any detail. In this article, a classification (database) of the etiologies of epilepsy is proposed. In this scheme, the etiology of epilepsy is divided into four categories: idiopathic, symptomatic, provoked, and cryptogenic. These are defined and subcategories are proposed. A commentary addressing the following points is included: problems associated with assigning causation, symptomatic versus idiopathic epilepsy, focal versus generalized epilepsy, acquired epilepsy, acute symptomatic epilepsy, risk factor analysis, provoked epilepsy genetic and developmental epilepsy, and epilepsy as a disease not a symptom.
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