Journal
EPIDEMIOLOGY AND INFECTION
Volume 143, Issue 8, Pages 1719-1730Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268814002489
Keywords
Cost of disease; hospital costs; streptococcal infections; Streptococcus pyogenes; treatment costs
Funding
- Public Health England
- National Institute for Health Research Biomedical Research Centre at Imperial College London
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The objective of this study was to estimate the direct financial costs of hospital care for management of invasive group A streptococcal (GAS) infections using hospital records for cases diagnosed in England. We linked laboratory-confirmed cases (n = 3696) identified through national surveillance to hospital episode statistics and reimbursement codes. From these codes we estimated the direct hospital costs of admissions. Almost all notified invasive GAS cases (92% of 3696) were successfully matched to a primary hospital admission. Of these, secondary admissions (within 30 days of primary admission) were further identified for 593 (17%). After exclusion of nosocomial cases (12%), the median costs of primary and secondary hospital admissions were estimated by subgroup analysis as 1984- pound 2212 pound per case, totalling 4.43- pound 6.34 pound million per year in England. With adjustment for unmatched cases this equated to 4.84- pound 6.93 pound million per year. Adults aged 16-64 years accounted for 48% of costs but only 40% of cases, largely due to an increased number of surgical procedures. The direct costs of hospital admissions for invasive GAS infection are substantial. These estimated costs will contribute to a full assessment of the total economic burden of invasive GAS infection as a means to assess potential savings through prevention measures.
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