Journal
EPIDEMIOLOGY AND INFECTION
Volume 139, Issue 6, Pages 807-817Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268811000185
Keywords
Clinical features; epidemiology; outcomes; vaccination; West Nile virus
Funding
- United States Department of Defense, Telemedicine and Advanced Technology Research Center (TexSHIELD) [W81XWH-07-2-0031]
- Natural Environment Research Council [CEH010021] Funding Source: researchfish
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West Nile virus (WNV) is now endemic in the USA. After the widespread surge of virus activity across the USA, research has flourished, and our knowledge base has significantly expanded over the past 10 years since WNV was first recognized in New York City. This article provides a review of the virology of WNV, history, epidemiology, clinical features, pathology of infection, the innate and adaptive immune response, host risk factors for developing severe disease, clinical sequelae following severe disease, chronic infection, and the future of prevention.
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