Journal
EPIDEMIOLOGY AND INFECTION
Volume 138, Issue 11, Pages 1630-1636Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268810000695
Keywords
Bangladesh; Nipah virus; person-to-person transmission
Funding
- Centers for Disease Control and Prevention (CDC), Atlanta
- U.S. National Institutes of Health, International Collaborations in Infectious Disease Research (ICIDR)
- Government of Bangladesh (GoB) through IHP-HNPRP
- John E. Fogarty International Center [2R01-TW005869]
- U.S. National Institutes of Health [AI57158, AI070411, AI067549]
- U.S. Department of Defense
- U.S. National Institutes of Health
- Government of Bangladesh
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In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 9.5%, OR undefined, P<0.001) and to have touched him (83% vs. 0%, OR undefined, P<0.001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.
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