Journal
EPIDEMIOLOGY AND INFECTION
Volume 138, Issue 9, Pages 1267-1273Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268809991452
Keywords
Body mass index; Chlamydia; C-reactive protein
Funding
- Ministry of Defence of Finland [717]
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Chlamydia pneumoniae infection is said to be associated with obesity. We studied the association between C. pneumoniae infection and inflammation and increased BM I in 891 Finnish military recruits. IgG seropositivity in arrival and departure serum samples during 6-12 months of military service was considered as persistence of antibodies and a possible indication of chronic infection. Persistently high C-reactive protein (CRP) level (elevated on arrival and departure) (OR 2.2, 95% CI 1.3-3.9), and persistent C. pneumoniae antibodies (OR 2.1, 95% CI 1.5-2.8) were significant risk factors for overweight (BMI >= 25 kg/m(2)). In addition, those who had persistent antibodies and persistently elevated CRP levels, or those who had either of them, had a significantly higher BMI (kg/m(2)) compared to those who had neither of them (25.8 vs. 24.6 vs. 23.5, respectively; P < 0.001). These results provide new information about the association between possible chronic C. pneumoniae infection and obesity in young men.
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