Journal
EPIDEMIOLOGY AND INFECTION
Volume 136, Issue 11, Pages 1556-1563Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268807000131
Keywords
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Funding
- National Natural Science Foundation [30630049]
- China National '973' Programme [2005CB52300]
- UK Department for Environment, Food and Rural Affairs (Defra) [SEV3500]
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Human rabies in China continues to increase exponentially, largely due to all inadequate veterinary infrastructure and poor vaccine coverage of naive dogs. We performed an epidemiological survey of rabies both in humans and animals, examined vaccine duality for animal use, evaluated the vaccination coverage in dogs, and checked the dog samples for the presence of rabies virus. The lack of surveillance in dog rabies, together with the low immunization coverage (up to 2.8 % in rural areas) and the high percentage of rabies virus prevalence (up to 6.4%) in dogs. suggests that the dog population is a continual threat for rabies transmission from dogs to humans in China. Results also indicated that the quality of rabies vaccines for animal use did not satisfy all of the requirements for all efficacious vaccine capable of fully eliminating rabies. These data Suggest that the factors noted above are highly correlated with the high incidence of human rabies in China.
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