Journal
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
Volume 18, Issue 1, Pages 8-12Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jsams.2013.11.008
Keywords
Oestrogen; Progesterone; Running; Iron deficiency
Categories
Funding
- University of Western Australia Research Development Award
Ask authors/readers for more resources
Objectives: The post-exercise interleuldn-6 (IL-6) and hepcidin response was investigated during the hormone-deplete and hormone-replete phases of an estradiol and progestogen regulated oral contraceptive cycle (OCC). Design: Counterbalanced, repeated measures cross-over study. Methods: Ten active female monophasic oral contraceptive pill (OCP) users completed two 40 min treadmill running trials at 75% of their pre-determined peak oxygen uptake velocity (VVO2peak). These trials were randomly performed in two specific phases of the OCC: (a) Day 2-4, representing a hormone-free withdrawal period (D-0); (b) Day 12-14, representing the end of the first week of active hormone therapy (D + 7). Venous blood samples were drawn pre-, post- and 3 h post-exercise. Results: In both trials, serum IL-6 was significantly elevated (p<0.05) immediately post-exercise, while serum hepcidin was significantly elevated (p<0.05) 3 h post-exercise, with no significant differences recorded between trials. Conclusions: These findings suggest that exercise performed during the different phases (D - 0 vs. D + 7) of a monophasic OCP regulated cycle does not alter exercise induced IL-6 or hepcidin production. As such, future studies looking to investigate similar variables post-exercise, may not need to 'control' for different phases of the OCC, provided participants are current monophasic OCP users. (C) 2013 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available