4.7 Article

Korea National Survey for Environmental Pollutants in the human body 2008: 1-hydroxypyrene, 2-naphthol, and cotinine in urine of the Korean population

Journal

ENVIRONMENTAL RESEARCH
Volume 118, Issue -, Pages 25-30

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.envres.2012.07.010

Keywords

Cotinine; 1-Hydorxypyrene; 2-Naphthol; Nicotine; Polycyclic aromatic hydrocarbons; Urinary metabolites

Funding

  1. National Institute of Environmental Research of Korea, as the Korea National Survey for Environmental Pollutants in the Human Body
  2. ACE program through the National Research Foundation of Korea (NRF) grant
  3. Korean Ministry of Education, Science and Technology (MEST) [20110028202]

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The Korea National Survey for Environmental Pollutants in the human body conducts representative Korean population studies, which were first initiated in 2005 in Korea. This study was conducted from 2008 to 2009 to determine the exposure levels of polycyclic aromatic hydrocarbons and nicotine in the Korean general population. The study population consisted of 4702 adult subjects from 196 sampling locations including coastal, rural, and urban areas. The urinary levels of 1-hydroxypyrene, 2-naphthol, and cotinine were measured for exposure of polycyclic aromatic hydrocarbons and nicotine. The geometric means of the urinary 1-hydroxypyrene, 2-naphthol and cotinine concentrations in the Korean general population were 0.15 mu g/L (95% confidence interval (CI): 0.13-0.17), 3.84 mu g/L (95% CI: 3.57-4.11) and 47.42 mu g/L (95% CI: 40.52-54.32) respectively. When these values were compared with reference ranges for the United States and Germany, the levels of 1-hydroxypyrene, 2-naphthol, and cotinine were very similar for Korea and Germany, however, these levels were slightly lower in the United States. This study is the first nationwide survey of exposure to polycyclic aromatic hydrocarbons and nicotine in Korea and provides a background reference range for exposure to polycyclic aromatic hydrocarbons and nicotine in the Korean general population. (c) 2012 Elsevier Inc. All rights reserved.

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