Journal
ENVIRONMENTAL POLLUTION
Volume 178, Issue -, Pages 147-151Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2013.03.002
Keywords
Cry proteins; Bt maize; Nematodes; Caenorhabditis elegans; Reproduction; Risk assessment
Categories
Funding
- German Ministry of Education and Research (BMBF) [0315215]
- National Institutes of Health
Ask authors/readers for more resources
The genetically modified maize MON89034 x MON88017 expresses different crystal (Cry) proteins with pesticidal activity against the European corn borer (Cry1.105; Cry2Ab2) and the Western corn root worm (Cry3Bb1). Non-target organisms, such as soil nematodes, might be exposed to the Cry proteins that enter the soil in course of crop growing. Therefore, the risk of those proteins for nematodes was assessed by testing their toxic effects on Caenorhabditis elegans. All three insecticidal Cry proteins showed dose-dependent inhibitory effects on C elegans reproduction (EC50: 0.12-0.38 mu mol L-1), however, at concentrations that were far above the expected soil concentrations. Moreover, a reduced toxicity was observed when Cry proteins were added jointly. A C elegans mutant strain deficient for receptors for the nematicidal Cry5B was also resistant against Cry1.105 and Cry2Ab2, suggesting that these Cry proteins bound to the same or similar receptors as nematicidal Cry proteins and thereby affect the reproduction of C elegans. (C) 2013 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available