Polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs) in breast milk from Zhejiang, China

Breast milk samples (n = 74) from the general maternal population of Zhejiang province were analyzed for polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), polychlorinated biphenyls (PCBs), and poly-brominated diphenyl ethers (PBDEs). Samples were divided into urban and rural groups. Mean Sigma PCDD/F, Sigma PCB and Sigma PBDE concentrations were 71.4 +/- 40.8, 42774 +/- 27841 and 2679 +/- 944 pg g(-1) lipid in the urban group and 38.6 +/- 38.1, 26546 +/- 11375 and 2731 +/- 1093 pg g(-1) lipid in the rural group, respectively. WHO-TEQ concentrations for dioxin-like PCBs and PCDD/Fs were 2.66 +/- 1.43 and 3.90 +/- 2.60 pg g(-1) lipid in the urban group and 1.83 +/- 0.93 and 2.27 +/- 1.55 pg g(-1) lipid in the rural group, respectively. Congener profiles for these pollutants were compared between human samples (adipose tissue and breast milk) and foodstuffs (seafood, hen eggs, and freshwater fish). Similar PCB and PCDD/F congener patterns were observed, suggesting that dietary intake is a significant source for human exposure to PCBs and PCDD/Fs. However, much lower PBDE congener levels were detected in breast milk than in foodstuffs, which implies that pathways other than dietary intake may also account for human exposure to PBDEs. (C) 2011 Elsevier Ltd. All rights reserved.