Related references
Note: Only part of the references are listed.A Coupled Population Balance Model and CFD Approach for the Simulation of Mixing Issues in Lab-Scale and Industrial Bioreactors
Jerome Morchain et al.
AICHE JOURNAL (2014)
Prelude to rational scale-up of penicillin production: a scale-down study
Guan Wang et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2014)
Flux response of glycolysis and storage metabolism during rapid feast/famine conditions in Penicillium chrysogenum using dynamic 13C labeling
Lodewijk de Jonge et al.
BIOTECHNOLOGY JOURNAL (2014)
Two- compartment processing as a tool to boost recombinant protein production
Mohammadhadi Jazini et al.
ENGINEERING IN LIFE SCIENCES (2014)
A dynamic two phase flow model for a pilot scale sodium borohydride hydrogen generation reactor
T. Sousa et al.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY (2014)
Kinetic models in industrial biotechnology - Improving cell factory performance
Joachim Almquist et al.
METABOLIC ENGINEERING (2014)
Process inhomogeneity leads to rapid side product turnover in cultivation of Corynebacterium glutamicum
Friedrich Kaess et al.
MICROBIAL CELL FACTORIES (2014)
Lost in Transition: Start-Up of Glycolysis Yields Subpopulations of Nongrowing Cells
Johan H. van Heerden et al.
SCIENCE (2014)
Coupling of Biokinetic and Population Balance Models to Account for Biological Heterogeneity in Bioreactors
Jerome Morchain et al.
AICHE JOURNAL (2013)
Scale-down studies for assessing the impact of different stress parameters on growth and product quality during animal cell culture
Alvin W. Nienow et al.
CHEMICAL ENGINEERING RESEARCH & DESIGN (2013)
CFD modelling of two-phase stirred bioreaction systems by segregated solution of the Euler-Euler model
M. Elqotbi et al.
COMPUTERS & CHEMICAL ENGINEERING (2013)
Dynamic process conditions in bioprocess development
Oliver Spadiut et al.
ENGINEERING IN LIFE SCIENCES (2013)
Investigation of the physiological response to oxygen limited process conditions of Pichia pastoris Mut+ strain using a two-compartment scale-down system
Bettina Lorantfy et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2013)
Glycolytic strategy as a tradeoff between energy yield and protein cost
Avi Flamholz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Real-time fluid dynamics investigation and physiological response for erythromycin fermentation scale-up from 50 L to 132 m3 fermenter
Xiang Zou et al.
BIOPROCESS AND BIOSYSTEMS ENGINEERING (2012)
A model for cellulase production from Trichoderma reesei in an airlift reactor
Rachid Bannari et al.
BIOTECHNOLOGY AND BIOENGINEERING (2012)
Multidimensional population balance model for the simulation of turbulent gas-liquid systems in stirred tank reactors
A. Buffo et al.
CHEMICAL ENGINEERING SCIENCE (2012)
CFD simulation of wood chip combustion on a grate using an Euler-Euler approach
D. Kurz et al.
COMBUSTION THEORY AND MODELLING (2012)
A novel impeller configuration to improve fungal physiology performance and energy conservation for cephalosporin C production
Yiming Yang et al.
JOURNAL OF BIOTECHNOLOGY (2012)
Substrate cycles in Penicillium chrysogenum quantified by isotopic non-stationary flux analysis
Zheng Zhao et al.
MICROBIAL CELL FACTORIES (2012)
Experimental methods and modeling techniques for description of cell population heterogeneity
R. Lencastre Fernandes et al.
BIOTECHNOLOGY ADVANCES (2011)
Simulation of dissolved CO2 gradients in a scale-down system: A metabolic and transcriptional study of recombinant Escherichia coli
Antonino Baez et al.
BIOTECHNOLOGY JOURNAL (2011)
A two-compartment bioreactor system made of commercial parts for bioprocess scale-down studies: Impact of oscillations on Bacillus subtilis fed-batch cultivations
Stefan Junne et al.
BIOTECHNOLOGY JOURNAL (2011)
An industrial perspective on bioreactor scale-down: What we can learn from combined large-scale bioprocess and model fluid studies
Henk Noorman
BIOTECHNOLOGY JOURNAL (2011)
Scale-down of penicillin production in Penicillium chrysogenum
Lodewijk P. de Jonge et al.
BIOTECHNOLOGY JOURNAL (2011)
Investigations on hydrodynamics and mass transfer in gas-liquid stirred reactor using computational fluid dynamics
Panneerselvam Ranganathan et al.
CHEMICAL ENGINEERING SCIENCE (2011)
Industrial Systems Biology
Jose Manuel Otero et al.
BIOTECHNOLOGY AND BIOENGINEERING (2010)
Local void fraction and bubble size distributions in cold-gassed and hot-sparged stirred reactors
Yuyun Bao et al.
CHEMICAL ENGINEERING SCIENCE (2010)
Scale-down simulators for metabolic analysis of large-scale bioprocesses
Peter Neubauer et al.
CURRENT OPINION IN BIOTECHNOLOGY (2010)
Origin and analysis of microbial population heterogeneity in bioprocesses
Susann Mueller et al.
CURRENT OPINION IN BIOTECHNOLOGY (2010)
Development and application of a differential method for reliable metabolome analysis in Escherichia coli
Hilal Taymaz-Nikerel et al.
ANALYTICAL BIOCHEMISTRY (2009)
Modelling of mass transfer in gas-liquid stirred tanks agitated by Rushton turbine and CD-6 impeller: A scale-up study
J. Gimbun et al.
CHEMICAL ENGINEERING RESEARCH & DESIGN (2009)
Dynamic 13C-tracer study of storage carbohydrate pools in aerobic glucose-limited Saccharomyces cerevisiae confirms a rapid steady-state turnover and fast mobilization during a modest stepup in the glucose uptake rate
Fredrick O. Aboka et al.
FEMS YEAST RESEARCH (2009)
Euler-Euler Modeling of Flow, Mass Transfer, and Chemical Reaction in a Bubble Column
Dongsheng Zhang et al.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2009)
Determination of the cytosolic free NAD/NADH ratio in Saccharomyces cerevisiae under steady-state and highly dynamic conditions
Andre B. Canelas et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
Three-dimensional mathematical modeling of dispersed two-phase flow using class method of population balance in bubble columns
Rachid Bannari et al.
COMPUTERS & CHEMICAL ENGINEERING (2008)
A metabolome study of the steady-state relation between central metabolism, amino acid biosynthesis and penicillin production in Penicillium chrysogenum
Uly Nasution et al.
METABOLIC ENGINEERING (2008)
Hydrodynamics of bubble column reactors at high gas velocity: Experiments and computational fluid dynamics (CFD) Simulations
Mohan R. Rampure et al.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2007)
Increasing NADH oxidation reduces overflow metabolism in Saccharomyces cerevisiae
G. N. Vemuri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Systems biology of antibiotic production by microorganisms
J. Stefan Rokem et al.
NATURAL PRODUCT REPORTS (2007)
Modeling aerated fermenters with computational fluid dynamics
Pasi Moilanen et al.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2006)
Living with heterogeneities in bioreactors
Alvaro R. Lara et al.
MOLECULAR BIOTECHNOLOGY (2006)
Generating short-term kinetic responses of primary metabolism of Penicillium chrysogenum through glucose perturbation in the bioscope mini reactor
U. Nasution et al.
METABOLIC ENGINEERING (2006)
In vivo kinetics with rapid perturbation experiments in Saccharomyces cerevisiae using a second-generation BioScope
Mlawule R. Mashego et al.
METABOLIC ENGINEERING (2006)
Modeling the dynamics of E-coli populations in the three-dimensional turbulent field of a stirred-tank bioreactor -: A structured-segregated approach
Alexei Lapin et al.
CHEMICAL ENGINEERING SCIENCE (2006)
Measurement of intracellular metabolites of primary metabolism and adenine nucleotides in chemostat cultivated Penicillium chrysogenum
U Nasution et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
CFD modeling of gas dispersion and bubble size in a double turbine stirred tank
F Kerdouss et al.
CHEMICAL ENGINEERING SCIENCE (2006)
Modelling strategies for the industrial exploitation of lactic acid bacteria
B Teusink et al.
NATURE REVIEWS MICROBIOLOGY (2006)
Approximative kinetic formats used in metabolic network modeling
JJ Heijnen
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Culture of Escherichia coli under dissolved oxygen gradients simulated in a two-compartment scale-down system:: Metabolic response and production of recombinant protein
EA Sandoval-Basurto et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
MIRACLE:: mass isotopomer ratio analysis of U-13C-labeled extracts.: A new method for accurate quantification of changes in concentrations of intracellular metabolites
MR Mashego et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Robustness of cellular functions
J Stelling et al.
CELL (2004)
Dynamic behavior of microbial populations in stirred bioreactors simulated with Euler-Lagrange methods:: Traveling along the lifelines of single cells
A Lapin et al.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2004)
Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses
D Visser et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Pulsed addition of limiting-carbon during Aspergillus oryzae fermentation leads to improved productivity of a recombinant enzyme
S Bhargava et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Cell population modelling of yeast glycolytic oscillations
MA Henson et al.
BIOCHEMICAL JOURNAL (2002)
Dynamic modeling of the central carbon metabolism of Escherichia coli
C Chassagnole et al.
BIOTECHNOLOGY AND BIOENGINEERING (2002)
Scale-down model to simulate spatial pH variations in large-scale bioreactors
A Amanullah et al.
BIOTECHNOLOGY AND BIOENGINEERING (2001)
Physiological responses to mixing in large scale bioreactors
SO Enfors et al.
JOURNAL OF BIOTECHNOLOGY (2001)
Mixing in large-scale vessels stirred with multiple radial or radial and axial up-pumping impellers:: modelling and measurements
P Vrábel et al.
CHEMICAL ENGINEERING SCIENCE (2000)
Effect of cellular interaction on glycolytic oscillations in yeast: a theoretical investigation
J Wolf et al.
BIOCHEMICAL JOURNAL (2000)
Share Paper
