Related references
Note: Only part of the references are listed.On-line multiple component analysis for efficient quantitative bioprocess development
Christian Dietzsch et al.
JOURNAL OF BIOTECHNOLOGY (2013)
Effects of Light Intensity on the Growth and Lipid Accumulation of Microalga Scenedesmus sp 11-1 Under Nitrogen Limitation
Junhan Liu et al.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2012)
The effects of pH oscillation on Lactobacillus rhamnosus batch cultivation
Janne Wallenius et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)
Quantitative analysis of media dilution rate effects on Methanothermobacter marburgensis grown in continuous culture on H2 and CO2
S. Rittmann et al.
BIOMASS & BIOENERGY (2012)
Industrial glucoamylase fed-batch benefits from oxygen limitation and high osmolarity
Lasse Pedersen et al.
BIOTECHNOLOGY AND BIOENGINEERING (2012)
Model-based analysis on the relationship of signal quality to real-time extraction of information in bioprocesses
Patrick Wechselberger et al.
BIOTECHNOLOGY PROGRESS (2012)
A dynamic fed batch strategy for a Pichia pastoris mixed feed system to increase process understanding
Denes Zalai et al.
BIOTECHNOLOGY PROGRESS (2012)
Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway
Florian W. Krainer et al.
MICROBIAL CELL FACTORIES (2012)
The benefits of being transient: isotope-based metabolic flux analysis at the short time scale
Katharina Noeh et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2011)
The effect of temperature and pH gradients on Lactobacillus rhamnosus gene expression of stress-related genes
Janne Wallenius et al.
BIOPROCESS AND BIOSYSTEMS ENGINEERING (2011)
Simulation of dissolved CO2 gradients in a scale-down system: A metabolic and transcriptional study of recombinant Escherichia coli
Antonino Baez et al.
BIOTECHNOLOGY JOURNAL (2011)
Scale-down/scale-up studies leading to improved commercial beer fermentation
Alvin W. Nienow et al.
BIOTECHNOLOGY JOURNAL (2011)
Editorial: Towards faster bioprocess development
Peter Neubauer
BIOTECHNOLOGY JOURNAL (2011)
Eukaryotic metabolism: Measuring compartment fluxes
Judith Wahrheit et al.
BIOTECHNOLOGY JOURNAL (2011)
A two-compartment bioreactor system made of commercial parts for bioprocess scale-down studies: Impact of oscillations on Bacillus subtilis fed-batch cultivations
Stefan Junne et al.
BIOTECHNOLOGY JOURNAL (2011)
An industrial perspective on bioreactor scale-down: What we can learn from combined large-scale bioprocess and model fluid studies
Henk Noorman
BIOTECHNOLOGY JOURNAL (2011)
Decrease of energy spilling in Escherichia coli continuous cultures with rising specific growth rate and carbon wasting
Kaspar Valgepea et al.
BMC SYSTEMS BIOLOGY (2011)
Interactions between P-limitation and different C conditions on the fatty acid composition of an extremophile microalga
Elly Spijkerman et al.
EXTREMOPHILES (2011)
Effect of post-induction substrate oscillation on recombinant alkaline phosphatase production expressed in Escherichia coli
Mohammadhadi Jazini et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2011)
Engineering CHO cell growth and recombinant protein productivity by overexpression of miR-7
N. Barron et al.
JOURNAL OF BIOTECHNOLOGY (2011)
A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains
Christian Dietzsch et al.
MICROBIAL CELL FACTORIES (2011)
Heterologous production of active ribonuclease inhibitor in Escherichia coli by redox state control and chaperonin coexpression
Juozas Siurkus et al.
MICROBIAL CELL FACTORIES (2011)
A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris
Christian Dietzsch et al.
MICROBIAL CELL FACTORIES (2011)
Stock culture heterogeneity rather than new mutational variation complicates short-term cell physiology studies of Escherichia coli K-12 MG1655 in continuous culture
Ranno Nahku et al.
MICROBIOLOGY-SGM (2011)
Development of a fermentation process based on a defined medium for the production of pregallidermin, a nontoxic precursor of the lantibiotic gallidermin
Giovanni Medaglia et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
Mixed culture polyhydroxyalkanoates production from sugar molasses: The use of a 2-stage CSTR system for culture selection
M. G. E. Albuquerque et al.
BIORESOURCE TECHNOLOGY (2010)
Process Optimization of the Integrated Synthesis and Secretion of Ectoine and Hydroxyectoine Under Hyper/Hypo-Osmotic Stress
C. Fallet et al.
BIOTECHNOLOGY AND BIOENGINEERING (2010)
Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase
Kaspar Valgepea et al.
BMC SYSTEMS BIOLOGY (2010)
PAT method to gather bioprocess parameters in real-time using simple input variables and first principle relationships
Patrick Wechselberger et al.
CHEMICAL ENGINEERING SCIENCE (2010)
Scale-down simulators for metabolic analysis of large-scale bioprocesses
Peter Neubauer et al.
CURRENT OPINION IN BIOTECHNOLOGY (2010)
Metabolic engineering of sucrose utilizing Escherichia coli for polyhydroxybutyrate production
Y. Arifin et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Specific growth rate dependent transcriptome profiling of Escherichia coli K12 MG1655 in accelerostat cultures
Ranno Nahku et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Catching prompt metabolite dynamics in Escherichia coli with the BioScope at oxygen rich conditions
Marjan De Mey et al.
METABOLIC ENGINEERING (2010)
High cell density cultivation and recombinant protein production with Escherichia coli in a rocking- motion- type bioreactor
Julia Glazyrina et al.
MICROBIAL CELL FACTORIES (2010)
Production of polyhydroxyalkanoates in open, mixed cultures from a waste sludge stream containing high levels of soluble organics, nitrogen and phosphorus
Fernando Morgan-Sagastume et al.
WATER RESEARCH (2010)
Quasi steady state growth of Lactococcus lactis in glucose-limited acceleration stat (A-stat) cultures
Kaarel Adamberg et al.
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY (2009)
The pH Shift and Precursor Feeding Strategy in a Low-Toxicity FR-008/Candicidin Derivative CS103 Fermentation Bioprocess by a Mutant of Streptomyces sp FR-008
Xiangzhao Mao et al.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2009)
Enrichment of a Mixed Bacterial Culture with a High Polyhydroxyalkanoate Storage Capacity
Katja Johnson et al.
BIOMACROMOLECULES (2009)
Fast Dynamic Response of the Fermentative Metabolism of Escherichia coli to Aerobic and Anaerobic Glucose Pulses
Alvaro R. Lara et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
A methodological approach to scaling up fermentation and primary recovery processes to the manufacturing scale for vaccine production
Timothy S. Lee
VACCINE (2009)
Metabolic flux analysis in Escherichia coli by integrating isotopic dynamic and isotopic stationary 13C labeling data
Jochen Schaub et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
In Vivo Dynamics of Glycolysis in Escherichia coli Shows Need for Growth-Rate Dependent Metabolome Analysis
Jochen Schaub et al.
BIOTECHNOLOGY PROGRESS (2008)
Energetic and metabolic transient response of Saccharomyces cerevisiae to benzoic acid
M. T. A. P. Kresnowati et al.
FEBS JOURNAL (2008)
Quantitative physiological study of the fast dynamics in the intracellular pH of Saccharomyces cerevisiae in response to glucose and ethanol pulses
M. T. A. P. Kresnowati et al.
METABOLIC ENGINEERING (2008)
High cell density media for Escherichia coli are generally designed for aerobic cultivations -: consequences for large-scale bioprocesses and shake flask cultures
Jaakko Soini et al.
MICROBIAL CELL FACTORIES (2008)
Process Analytical Technology (PAT):: Batch-to-batch reproducibility of fermentation processes by robust process operational design and control
S. Gnoth et al.
JOURNAL OF BIOTECHNOLOGY (2007)
Citric acid production from sucrose using a recombinant strain of the yeast Yarrowia lipolytica
Andre Foerster et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2007)
High yield of mannosylglycerate production by upshock fermentation and bacterial milking of trehalose-deficient mutant Thermus thermophilus RQ-1
K. Egorova et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2007)
A portable anaerobic microbioreactor reveals optimum growth conditions for the methanogen Methanosaeta concilii
Benjamin Steinhaus et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)
Recent advances in polyhydroxyalkanoate production by mixed aerobic cultures: From the substrate to the final product
Joao M. L. Dias et al.
MACROMOLECULAR BIOSCIENCE (2006)
Living with heterogeneities in bioreactors
Alvaro R. Lara et al.
MOLECULAR BIOTECHNOLOGY (2006)
Generating short-term kinetic responses of primary metabolism of Penicillium chrysogenum through glucose perturbation in the bioscope mini reactor
U. Nasution et al.
METABOLIC ENGINEERING (2006)
Process parameter shifting:: Part I.: Effect of DOT, pH, and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled batch bioreactors
Evelyn Trummer et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Process parameter shifting:: Part II.: Biphasic cultivation -: A tool for enhancing the volumetric productivity of batch processes using Epo-Fc expressing CHO cells
Evelyn Trummer et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
In vivo kinetics with rapid perturbation experiments in Saccharomyces cerevisiae using a second-generation BioScope
Mlawule R. Mashego et al.
METABOLIC ENGINEERING (2006)
Measurement of intracellular metabolites of primary metabolism and adenine nucleotides in chemostat cultivated Penicillium chrysogenum
U Nasution et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Short-term metabolome dynamics and carbon, electron, and ATP balances in chemostat-grown Saccharomyces cerevisiae CEN.PK 113-7D following a glucose pulse
Liang Wu et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Effect of nitrogen limitation on the ergosterol production by fed-batch culture of Saccharomyces cerevisiae
F Shang et al.
JOURNAL OF BIOTECHNOLOGY (2006)
Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system
AR Lara et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Transcriptional response of steady-state yeast cultures to transient perturbations in carbon source
M Ronen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
On adaptive optimal input design: A bioreactor case study
J. D. Stigter et al.
AICHE JOURNAL (2006)
When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation
M. T. A. P. Kresnowati et al.
MOLECULAR SYSTEMS BIOLOGY (2006)
Stable hybridoma cultivation in a pilot-scale acoustic perfusion system: Long-term process performance and effect of recirculation rate
MCF Dalm et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Production of xylitol from D-xylose by recombinant Lactococcus lactis
A Nyyssölä et al.
JOURNAL OF BIOTECHNOLOGY (2005)
Transient increase of ATP as a response to temperature up-shift in Escherichia coli -: art. no. 9
J Soini et al.
MICROBIAL CELL FACTORIES (2005)
Effect of cycle time on fungal morphology, broth rheology, and recombinant enzyme productivity during pulsed addition of limiting carbon source
S Bhargava et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Interesting physiological response of the osmophilic yeast Candida krusei to heat shock
HJ Liu et al.
ENZYME AND MICROBIAL TECHNOLOGY (2005)
Production of β-galactosidase by Kluyveromyces marxianus under oscillating dissolved oxygen tension
G Cortés et al.
PROCESS BIOCHEMISTRY (2005)
Monitoring population dynamics of the thermophilic Bacillus licheniformis CCMI 1034 in batch and continuous cultures using multi-parameter flow cytometry
A Reis et al.
JOURNAL OF BIOTECHNOLOGY (2005)
Optimization of biomass, vitamins, and carotenoid yield on light energy in a flat-panel reactor using the A-stat technique
MJ Barbosa et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Aeration strategy:: a need for very high ethanol performance in Saccharomyces cerevisiae fed-batch process
S Alfenore et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2004)
Effects of oxidative stress on production of heterologous and native protein, and culture morphology in batch and chemostat cultures of Aspergillus niger (B1-D)
ZH Bai et al.
ENZYME AND MICROBIAL TECHNOLOGY (2004)
Heterogeneous conditions in dissolved oxygen affect N-glycosylation but not productivity of a monoclonal antibody in hybridoma cultures
JA Serrato et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Production of phytase (myo-inositolhexakisphosphate phosphohydrolase) by Aspergillus niger van Teighem in laboratory-scale fermenter
P Vats et al.
BIOTECHNOLOGY PROGRESS (2004)
Metabolic load of recombinant protein production:: Inhibition of cellular capacities for glucose uptake and respiration after induction of a heterologous gene in Escherichia coli
P Neubauer et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Monoseptic cultivation of phototrophic microorganisms - development and scale-up of a photobioreactor system with thermal sterilization
C Walter et al.
BIOMOLECULAR ENGINEERING (2003)
Reconstruction of the O2 uptake rate and CO2 evolution rate on a time scale of seconds
HHJ Bloemen et al.
AICHE JOURNAL (2003)
Optimisation of cultivation parameters in photobiore actors for microalgae cultivation using the A-stat technique
MJ Barbosa et al.
BIOMOLECULAR ENGINEERING (2003)
Physiological responses of chemostat cultures of Aspergillus niger (B1-D) to simulated and actual oxidative stress
ZH Bai et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Quantitative comparison of transient growth of Saccharomyces cerevisiae, Saccharomyces kluyveri, and Kluyveromyces lactis
C Herwig et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Determination of in vivo oxygen uptake and carbon dioxide evolution rates from off-gas measurements under highly dynamic conditions
L Wu et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Limiting factors in Escherichia coli fed-batch production of recombinant proteins
AM Sandén et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Strategies for improved dCO(2) removal in large-scale fed-batch cultures
SS Mostafa et al.
BIOTECHNOLOGY PROGRESS (2003)
Optimal control of (bio-)chemical reactors: generic properties of time and space dependent optimization
IY Smets et al.
MATHEMATICS AND COMPUTERS IN SIMULATION (2002)
Rapid sampling for analysis of in vivo kinetics using the BioScope: A system for continuous-pulse experiments
D Visser et al.
BIOTECHNOLOGY AND BIOENGINEERING (2002)
The response of GS-NS0 myeloma cells to single and multiple pH perturbations
JJ Osman et al.
BIOTECHNOLOGY AND BIOENGINEERING (2002)
Metabolic flux analysis of Candida tropicalis growing on xylose in an oxygen-limited chemostat
T Granström et al.
METABOLIC ENGINEERING (2002)
Controlled transient changes reveal differences in metabolite production in two Candida yeasts
T Granstrom et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2002)
On-line stoichiometry and identification of metabolic state under dynamic process conditions
C Herwig et al.
BIOTECHNOLOGY AND BIOENGINEERING (2001)
Determination of the maximum specific uptake capacities for glucose and oxygen in glucose-limited fed-batch cultivations of Escherichia coli
HY Lin et al.
BIOTECHNOLOGY AND BIOENGINEERING (2001)
Physiological responses to mixing in large scale bioreactors
SO Enfors et al.
JOURNAL OF BIOTECHNOLOGY (2001)
Scale-up of tubular photobioreactors
EM Molina et al.
JOURNAL OF APPLIED PHYCOLOGY (2000)
Role of proteases in autolysis of Penicillium chrysogenum chemostat cultures in response to nutrient depletion
M McIntyre et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2000)
Growth kinetics of Escherichia coli with galactose and several other sugars in carbon-limited chemostat culture
U Lendenmann et al.
CANADIAN JOURNAL OF MICROBIOLOGY (2000)