Journal
ENDOCRINE JOURNAL
Volume 56, Issue 3, Pages 425-433Publisher
JAPAN ENDOCRINE SOC
DOI: 10.1507/endocrj.K08E-222
Keywords
resistin; adiponectin; leptin; menstrual cycle; reproduction
Categories
Ask authors/readers for more resources
This study investigated the serum levels of resistin, adiponectin and leptin during the physiological menstrual cycle. Sixteen women (age: 19-30 years; body mass index: 19.46-24.9) with regular menstrual cycles participated. Fasting blood samples were collected on alternate days throughout a full menstrual cycle. Mean resistin concentrations were slightly higher during the luteal phase (5.30 +/- 0.23 ng/ml) compared to the follicular (4.68 +/- 0.07 ng/ml) and midcycle (4.86 +/- 0.09 ng/ml) phases (p=0.032). Mean leptin concentrations during the follicular phase (18.14 +/- 0.28 ng/ml) were significantly lower compared to the midcycle (21.79 +/- 0.29 ng/ml, p=0.006) and luteal phases (23.75 +/- 0.64 ng/ml, p<0.001). The variation of adiponectin concentrations throughout the menstrual cycle was not significant. According to the results, circulating resistin, likewise leptin concentrations vary significantly during the physiological menstrual cycle presenting with higher values during the luteal phase. This pattern, although its physiological importance is not clear, suggests that resistin, likewise to leptin, may have a role in the regulation of cyclic female reproductive functions. The stable adiponectin concentrations throughout the menstrual cycle indicate that this adipokine probably does not play a considerable role in female reproductive functions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available