Related references
Note: Only part of the references are listed.The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations
Kelley S. Yan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Mutant BRAF Melanomas-Dependence and Resistance
Poulikos I. Poulikakos et al.
CANCER CELL (2011)
Novel Synthetic Antagonists of Canonical Wnt Signaling Inhibit Colorectal Cancer Cell Growth
Jo Waaler et al.
CANCER RESEARCH (2011)
Function and regulation of the Mediator complex
Ronald C. Conaway et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
Felipe C. Geyer et al.
MODERN PATHOLOGY (2011)
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
Hua Tian et al.
NATURE (2011)
Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation
Paul B. Chapman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
FZD7 has a critical role in cell proliferation in triple negative breast cancer
L. Yang et al.
ONCOGENE (2011)
Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/β-catenin signaling
Alix Scholer-Dahirel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway
Foster C. Gonsalves et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome
Andrey I. Khramtsov et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells
Jenny Yeung et al.
CANCER CELL (2010)
Bcl9/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem Cell Traits in Colon Epithelium and Adenocarcinomas
Juergen Deka et al.
CANCER RESEARCH (2010)
Colorectal Tumors Are Effectively Eradicated by Combined Inhibition of β-Catenin, KRAS, and the Oncogenic Transcription Factor ITF2
Luca Mologni et al.
CANCER RESEARCH (2010)
Targeting Wnt Signaling: Can We Safely Eradicate Cancer Stem Cells?
Fumi Takahashi-Yanaga et al.
CLINICAL CANCER RESEARCH (2010)
RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon Cancer
Ji Min Lee et al.
MOLECULAR CELL (2010)
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
Curtis A. Thorne et al.
NATURE CHEMICAL BIOLOGY (2010)
The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
Yingzi Wang et al.
SCIENCE (2010)
Small Molecule Inhibitors of Wnt/β-Catenin/Lef-1 Signaling Induces Apoptosis in Chronic Lymphocytic Leukemia Cells In Vitro and In Vivo
Rajesh Kumar Gandhirajan et al.
NEOPLASIA (2010)
WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
Don X. Nguyen et al.
CELL (2009)
β-Catenin Small Interfering RNA Successfully Suppressed Progression of Multiple Myeloma in a Mouse Model
Eishi Ashihara et al.
CLINICAL CANCER RESEARCH (2009)
Targeted Radionuclide Therapy Using a Wnt-Targeted Replicating Adenovirus Encoding the Na/I Symporter
Inge Peerlinck et al.
CLINICAL CANCER RESEARCH (2009)
Cancer stem cells: never Wnt away from the niche
Ilaria Malanchi et al.
CURRENT OPINION IN ONCOLOGY (2009)
Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells
Katharina Salome Minke et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2009)
Discovery and Characterization of a Small Molecule Inhibitor of the PDZ Domain of Dishevelled
David Grandy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Shih-Min A. Huang et al.
NATURE (2009)
Inhibition of Wnt signaling by Dishevelled PDZ peptides
Yingnan Zhang et al.
NATURE CHEMICAL BIOLOGY (2009)
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
Baozhi Chen et al.
NATURE CHEMICAL BIOLOGY (2009)
β-Catenin hits chromatin: regulation of Wnt target gene activation
Christian Mosimann et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma
G. Akiri et al.
ONCOGENE (2009)
The Internally Truncated LRP5 Receptor Presents a Therapeutic Target in Breast Cancer
Peyman Bjoerklund et al.
PLOS ONE (2009)
Glycogen synthase kinase 3β missplicing contributes to leukemia stem cell generation
Annelie E. Abrahamsson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth
Yutaka Matsuda et al.
BREAST CANCER RESEARCH (2009)
Pygopus and the Wnt signaling pathway: a diverse set of connections
Shannon Jessen et al.
BIOESSAYS (2008)
Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling
Ilaria Malanchi et al.
NATURE (2008)
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
Ron Firestein et al.
NATURE (2008)
Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo
Chen Zhao et al.
CANCER CELL (2007)
SiRNA-mediated β-catenin knockdown in human hepatoma cells results in decreased growth and survival
Gang Zeng et al.
NEOPLASIA (2007)
Mechanistic insights from structural studies of β-catenin and its binding partners
Wenqing Xu et al.
JOURNAL OF CELL SCIENCE (2007)
CDK8 is a stimulus-specific positive coregulator of p53 target genes
Aaron Joseph Donner et al.
MOLECULAR CELL (2007)
The soluble Wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
Venita I. DeAlmeida et al.
CANCER RESEARCH (2007)
Wilms tumor suppressor WTX negatively regulates WNT/β-catenin signaling
Michael B. Major et al.
SCIENCE (2007)
The many ways of Wnt in cancer
Paul Polakis
CURRENT OPINION IN GENETICS & DEVELOPMENT (2007)
An antagonist of dishevelled protein-protein interaction suppresses β-catenin-dependent tumor cell growth
Naoaki Fujii et al.
CANCER RESEARCH (2007)
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
Jason I. Herschkowitz et al.
GENOME BIOLOGY (2007)
CK2 controls the recruitment of Wnt regulators to target genes in vivo
Song Wang et al.
CURRENT BIOLOGY (2006)
Crystal structure of a β-catenin/BCL9/Tcf4 complex
James Sampietro et al.
MOLECULAR CELL (2006)
Wnt signaling: is the party in the nucleus?
Karl Willert et al.
GENES & DEVELOPMENT (2006)
Casein kinase 1γ couples Wnt receptor activation to cytoplasmic signal transduction
G Davidson et al.
NATURE (2005)
Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954
AN Lukashev et al.
HUMAN GENE THERAPY (2005)
ICG-001, A Novel Small Molecule Regulator of TCF/β-Catenin Transcription
Masakatsu Eguchi et al.
MEDICINAL CHEMISTRY (2005)
Wnt signalling in stem cells and cancer
T Reya et al.
NATURE (2005)
The links between axin and carcinogenesis
S Salahshor et al.
JOURNAL OF CLINICAL PATHOLOGY (2005)
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer
L Lammi et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
F Kuhnert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
CHM Jamieson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
A Bafico et al.
CANCER CELL (2004)
β-catenin and p53 analyses of a breast carcinoma tissue microarray
GG Chung et al.
CANCER (2004)
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
M Lepourcelet et al.
CANCER CELL (2004)
Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex
Y Xing et al.
GENES & DEVELOPMENT (2003)
A protein knockdown strategy to study the function of β-catenin in tumorigenesis -: art. no. 10
F Cong et al.
BMC MOLECULAR BIOLOGY (2003)
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
D Pinto et al.
GENES & DEVELOPMENT (2003)
Repeated observation of breast tumor subtypes in independent gene expression data sets
T Sorlie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
M van de Wetering et al.
CELL (2002)
The crystal structure of the β-catenin/ICAT complex reveals the inhibitory mechanism of ICAT
TA Graham et al.
MOLECULAR CELL (2002)
ICAT inhibits β-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules
DL Daniels et al.
MOLECULAR CELL (2002)
Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
CM Liu et al.
CELL (2002)
Molecular mechanisms of β-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-β-catenin complex
KE Spink et al.
EMBO JOURNAL (2001)
β-catenin antisense treatment decreases β-catenin expression and tumor growth rate in colon carcinoma xenografts
DW Green et al.
JOURNAL OF SURGICAL RESEARCH (2001)
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
T Brabletz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion-independent manner
CJ Gottardi et al.
JOURNAL OF CELL BIOLOGY (2001)
The structure of the β-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by β-catenin
AH Huber et al.
CELL (2001)
Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway
M Brunori et al.
JOURNAL OF VIROLOGY (2001)
Regulation of Lef-mediated transcription and p53-dependent pathway by associating β-catenin with CBP/p300
M Miyagishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates
A Hecht et al.
EMBO JOURNAL (2000)
β-catenin, a novel prognostic marker for breast cancer:: Its roles in cyclin D1 expression and cancer progression
SY Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
S Satoh et al.
NATURE GENETICS (2000)
Share Paper
