Related references
Note: Only part of the references are listed.Low-Flow Sheathless Capillary Electrophoresis-Mass Spectrometry for Sensitive Glycoform Profiling of Intact Pharmaceutical Proteins
Rob Haselberg et al.
ANALYTICAL CHEMISTRY (2013)
Hybrid Capillary/Microfluidic System for Comprehensive Online Liquid Chromatography-Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry
J. Scott Mellors et al.
ANALYTICAL CHEMISTRY (2013)
CE-MS for the analysis of intact proteins 2010-2012
Rob Haselberg et al.
ELECTROPHORESIS (2013)
CIEF method optimization: Development of robust and reproducible protein reagent characterization in the clinical immunodiagnostic industry
Ryan Bonn et al.
ELECTROPHORESIS (2013)
Analysis of recombinant monoclonal antibodies by capillary zone electrophoresis
Carlos E. Espinosa-de la Garza et al.
ELECTROPHORESIS (2013)
Characterization of Therapeutic Monoclonal Antibodies Reveals Differences Between In Vitro and In Vivo Time-Course Studies
Sheng Yin et al.
PHARMACEUTICAL RESEARCH (2013)
Capillary electrophoresis to investigate biopharmaceuticals and pharmaceutically-relevant binding properties
Sami El Deeb et al.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2013)
Analytical strategies for the characterization of therapeutic monoclonal antibodies
Szabolcs Fekete et al.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2013)
High-resolution MS for structural characterization of protein therapeutics: advances and future directions
Hui Wei et al.
BIOANALYSIS (2013)
Probing the conformational behavior of a monoclonal antibody with surfactant affinity capillary electrophoresis (SurfACE)
Brian T. Cooper et al.
ANALYST (2012)
High resolution separation methods for the determination of intact human erythropoiesis stimulating agents. A review
Michel Girard et al.
ANALYTICA CHIMICA ACTA (2012)
High-throughput analysis of therapeutic and diagnostic monoclonal antibodies by multicapillary SDS gel electrophoresis in conjunction with covalent fluorescent labeling
Akos Szekrenyes et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2012)
Charge Heterogeneity of Monoclonal Antibodies by Multiplexed Imaged Capillary Isoelectric Focusing Immunoassay with Chemiluminescence Detection
David A. Michels et al.
ANALYTICAL CHEMISTRY (2012)
Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics
Igor A. Kaltashov et al.
BIOTECHNOLOGY ADVANCES (2012)
Application of Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis to the Characterization of Ricin A-Chain Immunotoxins
Dong Hee Na et al.
CHROMATOGRAPHIA (2012)
Quantitative impurity analysis of monoclonal antibody size heterogeneity by CE-LIF: Example of development and validation through a quality-by-design framework
David A. Michels et al.
ELECTROPHORESIS (2012)
Applications of imaged capillary isoelectric focussing technique in development of biopharmaceutical glycoprotein-based products
Carrie L. Anderson et al.
ELECTROPHORESIS (2012)
Profiling of erythropoietin products by capillary electrophoresis with native fluorescence detection
Bregje J. de Kort et al.
ELECTROPHORESIS (2012)
Capillary electrophoresis-mass spectrometry methods for tryptic peptide mapping of therapeutic antibodies
Colin D. Whitmore et al.
ELECTROPHORESIS (2012)
Capillary gel electrophoresis for precise protein quantitation
Claudia Cianciulli et al.
ELECTROPHORESIS (2012)
Qualitative and quantitative evaluation of Simon™, a new CE-based automated Western blot system as applied to vaccine development
Richard R. Rustandi et al.
ELECTROPHORESIS (2012)
Immuno-magnetic beads-based extraction-capillary zone electrophoresis-deep UV laser-induced fluorescence analysis of erythropoietin
Heye Wang et al.
JOURNAL OF CHROMATOGRAPHY A (2012)
Development and validation of a rapid capillary zone electrophoresis method for determining charge variants of mAb
Ying Shi et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2012)
Utility of standard pharmacopeial and nonpharmacopeial methods in distinguishing folded, unfolded, and process variant forms of interferon α-2
John K. Mark et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Robustness of iCIEF methodology for the analysis of monoclonal antibodies: An interlaboratory study
Oscar Salas-Solano et al.
JOURNAL OF SEPARATION SCIENCE (2012)
Analytical characterization of ch14.18 A mouse-human chimeric disialoganglioside-specific therapeutic antibody
Gopalan Soman et al.
MABS (2012)
Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars
Steven A. Berkowitz et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Capillary electrophoresis-mass spectrometry for analysis of complex samples
Shuai Sherry Zhao et al.
PROTEOMICS (2012)
A rapid cIEF-ESI-MS/MS method for host cell protein analysis of a recombinant human monoclonal antibody
Guijie Zhu et al.
TALANTA (2012)
Use of capillary electrophoresis-sodium dodecyl sulfate to monitor disulfide scrambled forms of an Fc fusion protein during purification process
Suminda Hapuarachchi et al.
ANALYTICAL BIOCHEMISTRY (2011)
Identification of isomerization and racemization of aspartate in the Asp-Asp motifs of a therapeutic protein
Jennifer Zhang et al.
ANALYTICAL BIOCHEMISTRY (2011)
Characterization of glycation in an IgG1 by capillary electrophoresis sodium dodecyl sulfate and mass spectrometry
Timothy Kaschak et al.
ANALYTICAL BIOCHEMISTRY (2011)
High Throughput Profiling of Charge Heterogeneity in Antibodies by Microchip Electrophoresis
Hongling Han et al.
ANALYTICAL CHEMISTRY (2011)
Intercompany Study to Evaluate the Robustness of Capillary Isoelectric Focusing Technology for the Analysis of Monoclonal Antibodies
Oscar Salas-Solano et al.
CHROMATOGRAPHIA (2011)
Detection and identification of a serine to arginine sequence variant in a therapeutic monoclonal antibody
Diya Ren et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2011)
Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis
S. Kevin Li et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2011)
Assessment of Net Charge and Protein-Protein Interactions of Different Monoclonal Antibodies
Christian Lehermayr et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
A high-resolution capillary isoelectric focusing method for the determination of therapeutic recombinant monoclonal antibody
Jun Lin et al.
JOURNAL OF SEPARATION SCIENCE (2011)
Rapid analysis of charge variants of monoclonal antibodies with capillary zone electrophoresis in dynamically coated fused-silica capillary
Yan He et al.
JOURNAL OF SEPARATION SCIENCE (2011)
Recent advances of capillary electrophoresis in pharmaceutical analysis
Leena Suntornsuk
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2010)
Analysis of monoclonal antibody product heterogeneity resulting from alternate cleavage sites of signal peptide
Ruchi B. Kotia et al.
ANALYTICAL BIOCHEMISTRY (2010)
Characterization of Antibody Charge Heterogeneity Resolved by Preparative Immobilized pH Gradients
Charlie D. Meert et al.
ANALYTICAL CHEMISTRY (2010)
Analysis of Identity, Charge Variants, and Disulfide Isomers of Monoclonal Antibodies with Capillary Zone Electrophoresis in an Uncoated Capillary Column
Yan He et al.
ANALYTICAL CHEMISTRY (2010)
Capillary Electrophoretic Separation of Poly(ethylene glycol)-Modified Granulocyte-Colony Stimulating Factor
Kyung Soo Lee et al.
ARCHIVES OF PHARMACAL RESEARCH (2010)
Development of a capillary gel electrophoresis method for monitoring disulfide isomer heterogeneity in IgG2 antibodies
Nathan A. Lacher et al.
ELECTROPHORESIS (2010)
Charge heterogeneity of a therapeutic monoclonal antibody conjugated with a cytotoxic antitumor antibiotic, calicheamicin
Eiki Maeda et al.
JOURNAL OF CHROMATOGRAPHY A (2010)
A validated capillary electrophoresis method to check for batch-to-batch consistency during recombinant human glycosylated interleukin-7 production campaigns
Youssef Alahmad et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2010)
Method development and validation of capillary sodium dodecyl sulfate gel electrophoresis for the characterization of a monoclonal antibody
Junge Zhang et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2010)
Biopharmaceutical benchmarks 2010
Gary Walsh
NATURE BIOTECHNOLOGY (2010)
Comparison of different approaches for evaluation of the detection and quantitation limits of a purity method: A case study using a capillary isoelectrofocusing method for a monoclonal antibody
Izydor Apostol et al.
ANALYTICAL BIOCHEMISTRY (2009)
Challenges in monoclonal antibody-based therapies
Haritha Samaranayake et al.
ANNALS OF MEDICINE (2009)
CZE for glycoform profiling and quality assessment of recombinant human interleukin-7
Youssef Alahmad et al.
ELECTROPHORESIS (2009)
A systematic study in CIEF: Defining and optimizing experimental parameters critical to method reproducibility and robustness
Scott Mack et al.
ELECTROPHORESIS (2009)
Analysis of charge heterogeneities in mAbs using imaged CE
Xiaoping Z. He et al.
ELECTROPHORESIS (2009)
Characterization of deamidated peptide variants by micro-preparative capillary electrophoresis and mass spectrometry
Lynn A. Gennaro et al.
JOURNAL OF CHROMATOGRAPHY A (2009)
Charge-based analysis of antibodies with engineered cysteines From multiple peaks to a single main peak
Xiaoying (Nancy) Chen et al.
MABS (2009)
Performance comparison of capillary and agarose gel electrophoresis for the identification and characterization of monoclonal immunoglobulins
Christopher R. McCudden et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2008)
Twenty years of interface development for capillary electrophoresis-electrospray ionization-mass spectrometry
E. Jane Maxwell et al.
ANALYTICA CHIMICA ACTA (2008)
A study in glycation of a therapeutic recombinant humanized monoclonal antibody: Where it is, how it got there, and how it affects charge-based behavior
Cynthia Quan et al.
ANALYTICAL BIOCHEMISTRY (2008)
On-line CE-LIF-MS technology for the direct characterization of N-linked glycans from therapeutic antibodies
Lynn A. Gennaro et al.
ANALYTICAL CHEMISTRY (2008)
C-terminal lysine variants in fully human monoclonal antibodies: Investigation of test methods and possible causes
Lawrence W. Dick et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
Electrophoretic evidence for the presence of structural isoforms specific for the IgG2 isotype
Amy Guo et al.
ELECTROPHORESIS (2008)
Application of imaging capillary IEF for characterization and quantitative analysis of recombinant protein charge heterogeneity
Zoran Sosic et al.
ELECTROPHORESIS (2008)
Applications of CE SDS gel in development of biopharmaceutical antibody-based products
Richard R. Rustandi et al.
ELECTROPHORESIS (2008)
Pharmaceutical applications of isoelectric focusing on microchip with imaged UV detection
Marketa Vlckova et al.
JOURNAL OF CHROMATOGRAPHY A (2008)
Rapid and high-resolution glycoform profiling of recombinant human erythropoietin by capillary isoelectric focusing with whole column imaging detection
Peng Dou et al.
JOURNAL OF CHROMATOGRAPHY A (2008)
Non-covalent capillary coatings for protein separations in capillary electrophoresis
Charles A. Lucy et al.
JOURNAL OF CHROMATOGRAPHY A (2008)
Heterogeneity of monoclonal antibodies
Hongcheng Liu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Analysis of an antibody pharmaceutical, tocilizumab, by capillary electrophoresis using a carboxylated capillary
Atsushi Taga et al.
JOURNAL OF SEPARATION SCIENCE (2008)
Protein therapeutics: A summary and pharmacological classification
Benjamin Leader et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Fluorescent derivatization method of proteins for characterization by capillary elect rophoresis-sodium dodecyl sulfate with laser-induced fluorescence detection
David A. Michels et al.
ANALYTICAL CHEMISTRY (2007)
Evaluation of the iCE280 Analyzer as a potential high-throughput tool for formulation development
Ning Li et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2007)
Optimization and validation of a quantitative capillary electrophoresis sodium dodecyl sulfate method for quality control and stability monitoring of monoclonal antibodies
Oscar Salas-Solano et al.
ANALYTICAL CHEMISTRY (2006)
Capillary electrophoresis-mass spectrometry as a characterization tool for therapeutic proteins
Lynn A. Gennaro et al.
ANALYTICAL BIOCHEMISTRY (2006)
Glycoform characterization of erythropoietin combining glycan and intact protein analysis by capillary electrophoresis electrospray time-of-flight mass spectrometry
Elvira Balaguer et al.
ELECTROPHORESIS (2006)
Characterization of a novel modification to monoclonal antibodies: Thioether cross-link of heavy and light chains
GI Tous et al.
ANALYTICAL CHEMISTRY (2005)
Glycoform characterization of intact erythropoietin by capillary electrophoresis-electrospray-time of flight-mass spectrometry
C Neusüss et al.
ELECTROPHORESIS (2005)
Capillary electrophoretic characterization of PEGylated human parathyroid hormone with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
DH Na et al.
ANALYTICAL BIOCHEMISTRY (2004)
Determination of conjugation efficiency of antibodies and proteins to the superparamagnetic iron oxide nanoparticles by capillary electrophoresis with laser-induced fluorescence detection
FH Wang et al.
JOURNAL OF NANOPARTICLE RESEARCH (2003)
Capillary electrophoresis coupled to time of flight-mass spectrometry of therapeutic peptide hormones
V Sanz-Nebot et al.
ELECTROPHORESIS (2003)