4.5 Review

Advances in enantioselective separations using electromigration capillary techniques

Journal

ELECTROPHORESIS
Volume 30, Issue 1, Pages 100-132

Publisher

WILEY
DOI: 10.1002/elps.200800607

Keywords

Chiral additive; Chiral selector; Chiral stationary phase; Electromigration techniques; Enantioselective separation

Funding

  1. Austrian Christian Doppler Research Society
  2. AstraZeneca (Molndal, Sweden)
  3. Merck KGaA (Darmstadt, Germany)
  4. Sandoz (Kundl, Austria)

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The most recent literature dealing with enantioselective separations and stereoselective analyses of chiral entities including especially pharmaceuticals, phytochemicals, biochemicals, agrochemicals, fine chemicals and specific test compounds by electromigration techniques such as CE, MEKC, MEEKC, CEC and microchip CE is reviewed. The review covers literature from 2007 until mid-2008, i.e. studies that were published after the appearance of the latest review article on that topic in Electrophoresis by Gubitz and Schmid (see Electrophoresis 2007, 28, 114). Particular attention is given to the description of new chiral selector systems, studies on separation mechanisms and applications in the above-specified electromigration techniques.

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