4.5 Article

Insulator-based dielectrophoretic separation of small particles in a sawtooth channel

Journal

ELECTROPHORESIS
Volume 30, Issue 9, Pages 1441-1448

Publisher

WILEY
DOI: 10.1002/elps.200800833

Keywords

Dielectrophoresis; Particle trapping; Separation

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Insulator-based dielectrophoretic separation of small particles in a sawtooth channel is studied in the limit of dilute concentration. Pathlines for the movements of infinitesimal particles are constructed and the geometric changes of these pathlines are used to establish the criterion for blocking and trapping particles with different physical properties. The sharp corners of the sawtooth channel create much stronger dielectrophoretic force than channels with smooth corners for blocking particle movements. Particle blocking and trapping depend on particle properties and the geometry of the device. It is shown that once the channel geometric aspect ratios are specified, the blocking criterion depends on only a single dimensionless parameter C defined in terms of the particle mobility ratio (dielectrophoretic versus electrokinetic), the applied voltage and the spacing between the teeth. Selective blocking and trapping of particles can be realized by varying the geometry of the channel progressively. High-resolution separation can be achieved by tuning the differential in the parameter C to a desired level.

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