Square-wave voltammetric determination of pantoprazole using ex situ plated antimony-film electrode

The antimony film electrode (SbFE) was used for expedient measurement of pantoprazole, i.e. an important pharmaceutical substance. The SbFE was prepared ex situ on a supporting glassy carbon electrode and employed in direct square-wave voltammetric mode. After studying and optimizing several experimental parameters, the electrode exhibited an auspicious electroanalytical performance in Britton-Robinson buffer solution with the calculated LOD of 9.1 x 10(-7) mol L-1 and an excellent reproducibility with the RSD of +/- 0.8%. Actual applicability of the SbFE in organic electroanalysis was demonstrated via measuring low concentration levels of pantoprazole in a real pharmaceutical dosage form. (C) 2013 Elsevier Ltd. All rights reserved.