Gold electrodeposition on carbon nanotubes for the enhanced electrochemical detection of homocysteine

Homocysteine (HCys) has gathered considerable interest in recent years after being implicated in the pathogenesis of various clinical conditions. In this communication, nanomaterial modified carbon paste electrodes (CPEs) were optimized to detect HCys in solution. Electrodeposition of Au nanostructures on multi-walled carbon nanotubes (MWCNT) on a CPE surface provided a significant enhancement of the HCys oxidation signal. Possible application of the reported surface modification offers an ultra-sensitive platform for biosensing thiol-containing molecules. (C) 2011 Elsevier B.V. All rights reserved.