Journal
ELECTROCHEMICAL AND SOLID STATE LETTERS
Volume 11, Issue 8, Pages K81-K84Publisher
ELECTROCHEMICAL SOC INC
DOI: 10.1149/1.2937178
Keywords
-
Ask authors/readers for more resources
Electrografting provides a method for the direct (Si-C) covalent functionalization of silicon surfaces. In this work, cathodic electrografting of hexynoic acid to silicon nanowire surfaces and subsequent immobilization of bovine serum albumin (BSA) is demonstrated. Hexynoic acid was cathodically electrografted to dense arrays of silicon nanowires approximately 50-100 nm in diameter and 10 mu m in length. Protein immobilization was achieved via amidization reactions with carboxylic moieties of electrografted hexynoic acids. Results include chronoamperometric data from the electrografting process and verification of attachment using attenuated total reflectance Fourier transform infrared spectroscopy (FTIR) of electrografted hexynoic acid and immobilized BSA. In addition to FTIR analysis, covalently immobilized BSA was verified using fluorescence microscopy and solution-phase fluorescence. (C) 2008 The Electrochemical Society.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available