Journal
ELECTROANALYSIS
Volume 24, Issue 5, Pages 1141-1146Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201200018
Keywords
Acetylsalicylic acid; Caffeine; Boron-doped diamond electrode; Voltammetry; Analytical methods
Categories
Funding
- Fundacao de Apoio a Pesquisa do Estado de Minas Gerais (FAPEMIG)
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
- Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)
Ask authors/readers for more resources
This work presents a simple, fast and low-cost method for simultaneous determination of acetylsalicylic acid (ASA), without alkaline hydrolysis and caffeine (CF) in pharmaceutical formulations using a boron-doped diamond as the working electrode through differential pulse voltammetry. A good repeatability was reached for 20 measurements, with a low relative standard deviation of less than 1.0?%. The calibration curves presented a great linear correlation coefficient for both drugs (R=0.999) with a limit of detection of 1.6X10-7 mol?L-1 for CF and 2.3X10-7 mol?L-1 for ASA. The system was validated in comparison with the official method.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
