4.5 Article

A Voltammetric Sensor Based on Modified Multiwall Carbon Nanotubes for Cysteamine Determination in the Presence of Tryptophan Using p-Aminophenol as a Mediator

Journal

ELECTROANALYSIS
Volume 22, Issue 21, Pages 2558-2568

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201000270

Keywords

Cysteamine; Tryptophan; Carbon nanotubes; p-Aminophenol; Electrocatalytic effect; Voltammetry

Funding

  1. Isfahan University of Technology (IUT) Research Council
  2. Center of Excellence in Sensor and Green Chemistry

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Determination of cysteamine and tryptophan is described by electrochemical methods using p-aminophenol-multiwall carbon nanotubes paste electrode. Cysteamine and tryptophan in mixture can each be measured independently from each other with a potential difference of 600 mV. The results showed that the electrocatalytic currents increased linearly with cysteamine and tryptophan concentrations over the ranges 0.5-300 mu mol L-1 and 10.0-650 mu mol L-1, respectively. The detection limits for cysteamine and tryptophan are found to be 0.14 and 5.9 mu mol L-1, respectively. The proposed method is successfully employed for the determination of cysteamine in both capsule and urine samples.

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