Journal
ELECTROANALYSIS
Volume 20, Issue 11, Pages 1263-1266Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.200804177
Keywords
curcumin; differential pulse adsorptive stripping voltammetry; carbon paste electrode; hanging mercury drop electrode
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Curcumin (CU) shows a wide range of pharmacological properties including antioxidant, anti-inflammatory, and antitumor effects. In order to understand the chemical basis of different activities of curcumin, we have studied the oxidation and reduction of curcumin. Based on cyclic and differential pulse voltammetric methods, using carbon paste and hanging mercury drop electrodes, in the present study we tested different parameters to optimize the conditions for the determination of curcumin and its electrochemical characteristics. Better results were obtained via differential pulse voltammetry using carbon paste electrode. Curcumin yields well-defined differential pulse voltammetric responses with well-defined oxidation (in the potential region of 0.3-0.6 V, vs. Ag/AgCl) and reduction (at 0.3 V) peaks using carbon paste electrode.
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