Journal
JOURNAL OF PHYSICAL ORGANIC CHEMISTRY
Volume 28, Issue 8, Pages 527-535Publisher
WILEY
DOI: 10.1002/poc.3433
Keywords
associates; molecular recognition; proteins; supramolecular chemistry; synthetic receptors; thiacalix[4]arenes
Categories
Funding
- Russian Federation [CP-1753.2012.4]
Ask authors/readers for more resources
The formation of supramolecular associates based on water-soluble p-tert-butylthiacalix[4]arenes with amino acids has been studied. It was shown that amphiphilic p-tert-butylthiacalix[4]arenes preferably formed supramolecular associates with aromatic -amino acids (tyrosine and tryptophan). Increasing size of the substituents of p-tert-butylthiacalix[4]arenes led to increase molecular weight of supramolecular associates based on the macrocycles and guest molecules. The spatial structures of p-tert-butylthiacalix[4]arenes and their associates with phenylalanine were studied by two-dimensional H-1-H-1 nuclear Overhauser effect NMR spectroscopy. The ability of aggregates based on p-tert-butylthiacalix[4]arenes and amino acids to effectively interact with bovine serum albumin with the formation of 7- to 8-nm nanoparticles was shown. Copyright (c) 2015 John Wiley & Sons, Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available