Journal
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Volume 73, Issue 8, Pages 1884-1889Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2010.09.005
Keywords
Antioxidant enzymes; CAT; SOD; GPX; GST; GR; Metal; Fish Oreochromis niloticus
Categories
Funding
- Cukurova University [FEF2008BAP9]
Ask authors/readers for more resources
Antioxidant systems are known to be sensitive to metal exposures and are suggested to use in predicting sublethal metal toxicity. In this study, several antioxidant enzymes, such as catalase (CAT), superoxide dismutase (SOD), glutathione S-transferase (GST), glutathione peroxidase (GPX) and glutathione reductase (GR) were measured in the liver and kidney of Oreochromis niloticus exposed to sublethal concentrations of metals (Cd, Cu, Cr, Zn and Fe), using an acute (20 mu M, 48 h) or subchronic (10 mu M, 20 d) protocol. Beside the several increases of antioxidant enzyme activities, general inhibition was recorded after acute and chronic metal exposures. Results indicated that there were variations in responses of the enzymes to metal exposures, depending upon tissues, metals and exposure types. This study emphasized that the antioxidant enzymes are very sensitive to metals as their activities altered significantly, suggesting they could be helpful in predicting sublethal metal toxicity and useful as an early warning tool in natural monitoring studies. (c) 2010 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available