Journal
EARLY HUMAN DEVELOPMENT
Volume 89, Issue 11, Pages 899-904Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.earlhumdev.2013.09.001
Keywords
Short bowel syndrome; Intestinal failure; Intestinal adaptation; Parenteral nutrition
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Short bowel syndrome (SBS) is a reduction in functioning bowel length which is most often a result of surgical resection. Risk factors in the neonatal period include necrotising enterocolitis, small bowel atresia and gastroschisis. With increasing survival of preterm infants there is an increase in incidence. Management is dependent on the use of parenteral nutrition to maintain fluid and electrolyte homeostasis and promote growth and development with the longer term aim being to promote intestinal adaptation to achieve partial or complete enteral autonomy. In this review we discuss the incidence, aetiology, pathophysiology, medical and surgical treatments and outcome. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
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