Journal
EARLY HUMAN DEVELOPMENT
Volume 85, Issue 12, Pages 761-765Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.earlhumdev.2009.10.004
Keywords
aEEG; Amplitude-integrated EEG; Gestational age; Postmenstrual age; Maturation; Extrauterine life; Postnatal age; Preterm
Categories
Ask authors/readers for more resources
Objective: To study, the maturational changes of the amplitude-integrated electroencephalogram (aEEG) in preterm infants without neurological disorders and especially the influence of the duration of extrauterine life, over this process. Methods: 96 preterm infants, 25-34 weeks' gestational age (CA) at birth, clinically stable and without ultrasonographic evidence of neurological abnormalities, were studied. The aEEG recordings were obtained within 72 h of life and then weekly until discharge. Four aspects of each tracing (continuity. sleep-wake cycling, bandwidth, and lower border), were evaluated by visual analysis, applying pre-established criteria. Results: We analysed 624 aEEG recordings at postmenstrual age (PMA) of 25-42 weeks. With advanced CA the aEEG becomes more continuous (p: 0.022), it displays definite sleep-wake cycles (p: 0.011), and its bandwidth acquires the mature pattern (p: 0.012). A positive significant interaction of CA and PMA in the evolution of aEEG was found regarding continuity (p: 0.002), sleep-wake cycling (p: 0.002), and bandwidth (p: 0.02). Conclusion: The evolution of the aEEG tracing depends on both CA and PMA. The older the infants at birth the more mature the aEEG pattern. At the same PMA, preterm infants of lower CA display an advanced maturation of the aEEG comparing with others of higher GA. (c) 2009 Elsevier Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available