3.9 Article

Microwave Assisted Synthesis and Antimicrobial Activities of Some 2-Amino-4-aryl-3-cyano-6-(4′-hydroxy phenyl)-pyridines

Journal

E-JOURNAL OF CHEMISTRY
Volume 8, Issue 1, Pages 119-122

Publisher

WWW PUBL PTE
DOI: 10.1155/2011/984297

Keywords

Pyridine; Chalcone; Microwave assisted synthesis; Solventless

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4'-Hydroxy chalcones were treated with malononitrile in the presence of ammonium acetate under solventless microwave assisted condition to get 2-amino-4-aryl-3-cyano-6-(4'-hydroxy phenyl)-pyridines. The prepared compounds were screened for their antimicrobial activity; some of them have exhibited promising antimicrobial activity.

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